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Investigations are guided by clinical suspicion rather than routine panels: for example, thyroid function tests and ferritin may be checked if symptoms suggest deficiency or thyroid disease, while an androgen profile may be appropriate in women presenting with menstrual irregularity, hirsutism, or acne

Molecular DNA detection is another promising approach for early detection, although the technology is still under development [272]

Di Stasi SM, Giannantoni A, Stephen RL et al: A prospective, randomized study using transdermal electromotive administration of verapamil and dexamethasone for Peyronie's disease

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