Although the supplement is not FDA-approved, the official press release reads, "We spent years working with our medical advisory board to formulate Lemme GLP-1 Daily into the most effective and researched GLP-1 supplement on the market." According to Kardashian, "cutting-edge formulation uses both clinically studied and patented ingredients to increase GLP-1 levels in the body, naturally." Despite the claims, Kardashian's new supplement does not convince Lauren Harris-Pincus , MS, RDN, who told Page Six that this product is "unlikely" to work as semaglutide does
Appl Environ Microbiol
These factors that decrease GLP-1 correlate with the rise in obesity at a national and global level
Further, there is no indication of medical efficacy of these unregistered products with GLP-1 claims, in particular for weight-loss. The TGA urges consumer caution when purchasing medicines from unknown overseas websites, suggesting these products could be fake, contain incorrect or undisclosed and harmful ingredients, and may not meet the same standards of quality, safety and efficacy as those approved by the TGA for supply in Australia