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Submucosal gland mucus strand velocity is decreased in chronic rhinosinusitis

It is shown that IGFBP1 expression and secretion were significantly elevated in cancer cells, and secreted IGFBP-1 inhibits AKT1-mediated phosphorylation of ser27 of mitochondrial superoxide dismutase 2 (SOD2), thereby increasing the activity of SOD2 antioxidant enzymes

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