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In GetGoal-Duo-1, patients with inadequate glycemic control on metformin (average HbA 1c of 70 mmol/mol [8.6%]) were initiated and optimized on insulin glargine by titration to a target FPG range of 4.45.6 mmol/L over a 12-week period (study design shown in Fig

Microscopy acquisition and analysis were performed with the support of the Live Cell Imaging Core Facility of the Department of Clinical Research, coordinated by the Microscopy Imaging Center at the University of Bern, Switzerland

This potent antioxidant is capable of reducing the amount of melanin produced by inhibiting the activity of dopachrome tautomerase, an enzyme involved in melanin production