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The trade-off for this power and versatility is a significantly shorter operational life per charge, higher self-discharge , and a more complex management system required to ensure safety during charging and discharging

Seleninic or selenol intermediates generated from the oxidation/reduction of DSePA can follow the analogous catalytic steps as discussed for the native GPx enzyme in the earlier section to detoxify the hyperoxides by consuming the thiols [82, 83]