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Conlon JL

Biomedicine & Pharmacotherapy, 58, 173182

7.2 Polyphenols: orchestrators of redox balance and metabolic homeostasis Polyphenols mitigate ALD by chelating iron to block Fenton reaction-driven hydroxyl radical generation, while epigenetic modulation through SIRT1-mediated deacetylation of NF-B and histones further suppresses inflammation (Dini and Grumetto, 2022