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Ilic S, Drmic D, Zarkovic K, Kolenc D, Brcic L, Radic B, et al

Professor Ngs research contributions to AOD-9604 development include: Synthesis and characterization of the modified C-terminal growth hormone fragment with enhanced stability Design of the tyrosine N-terminal modification to improve peptide stability and half-life Preclinical studies demonstrating lipolytic effects in obese animal models Advancement of the peptide through multiple phases of clinical development Investigation of mechanisms underlying beta-3-adrenergic receptor modulation His work established the foundation for understanding peptide-based approaches to metabolic regulation, though clinical translation ultimately proved unsuccessful

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Food and Drug Administration) Separately, FDA documentation around the 503A bulks process shows AOD-9604s status has moved around as nominations were withdrawn and advisory committee discussions occurred