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Overall, mast cells have 50 200 granules in the cytoplasm of the cell, storing histamine, heparin, tryptase, cytokines, etc.[ref] The image below shows mast cell (stained purple) degranulation under a microscope.[ref] Allergies: Activating mast cells by Type 1 hypersensitivity In addition to reacting to antigens on pathogens, such as bacteria, the IgE can also be primed to link with antigens on proteins that are not pathogens, referred to as allergens

Thyroid Antibodies (TPOAb and TgAb) These markers tell us if the immune system is identifying the thyroid as a "threat." Thyroid Peroxidase Antibodies (TPOAb) and Thyroglobulin Antibodies (TgAb) are often elevated years before the TSH becomes abnormal

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