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At 72 weeks, the mean percentage change in weight was -20.9% with 15 mg of tirzepatide, as compared with -3.1% with placebo. SURMOUNT-1, per Jastreboff AM et al

These results imply that the anti-inflammatory and potentially anti-atherosclerotic effects of GLP-1 RAs are not attributable to improved adiposity, which is often associated with a low-grade inflammation [87]

559 A study utilizing microarray data from the human frontal cortex has shown that the expression of ZNT3 and ZNT4 significantly decreases with age, while the expression of ZIP1, ZIP9, and ZIP13 significantly increases

In multiple cancer cell lines, the erastin-induced LOOH increase is reduced after PRDX6 overexpression 25