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Furthermore, mitochondrial dysfunction and oxidative stress in AD patients are intricately intertwined, with evidence indicating mutual exacerbation, culminating in AD pathogenesis (130)

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The produced H 2 O 2 is converted to H 2 O either by ER peroxidases, which simultaneously recycle ER oxidoreductases and allow continuous protein folding, or by antioxidants such as GSH, which is then converted into GSSG

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