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Despite the great therapeutic potential of GLP-1R agonists, some challenges and shortcomings remain

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Weight Loss Distribution The results weren't just impressive on averagethey were consistent across the patient population: Weight Loss Thresholds Achieved (12mg dose): 5% weight loss: 94.6% of participants 10% weight loss: 91.3% of participants 15% weight loss: 83.2% of participants 20% weight loss: 73.4% of participants 25% weight loss: 58.6% of participants For comparison, FDA approval for obesity medications typically requires that at least 35% of patients achieve 5% weight loss

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