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A selenium-deficient diet induced the expression of miR-138-5p, which in turn suppressed the expression of SELENOM that has antioxidant function, and caused mitochondrial dysfunction and apoptosis of chondrocytes 128
Clinical trials systematically exclude pregnant women for ethical reasons, meaning safety information derives mainly from animal studies and inadvertent exposures reported through pharmacovigilance systems
In other cases, especially in people who are genetically susceptible, chemical injury may appear to trigger a wider immune response against melanocytes