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Alternately, dark brown or black urine can also be caused by some types of medication including quinine, which is used to prevent malarial infection, and metronidazole antibiotics

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Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen should be used cautiously and briefly, especially if you have diabetes, high blood pressure, or kidney concerns, because they can affect blood sugar control and renal function

Cell Viability Assay HepG2 cells were plated on collagen-coated 96-well plates at the density of 1 10 4 per well in 0.1 mL DMEM