Depending on severity and pattern, it lists dose adjustment, a temporary pause, switching to an oral formulation, or discontinuation as possibilities, and stresses these are decisions for the prescriber
These medications may include: corticotropin-releasing hormone doxorubicin (Lipodox, Doxil) glucocorticoids vasodilators, such as nitroglycerin (Rectiv, Nitro-Time, Nitrolingual) calcium channel blockers morphine (Arymo ER, MorphaBond ER, MS Contin) and other opiates amyl nitrite and butyl nitrite cholinergic drugs, such as metrifonate, and anthelmintic drugs bromocriptine (Parlodel, Cycloset) thyrotropin-releasing hormone tamoxifen (Soltamox) cyproterone acetate (not available in the U.S.) oral triamcinolone cyclosporine (Sandimmune, Neoral, Gengraf) rifampin (Rifadin) sildenafil citrate (Viagra, Revatio) Talk with a doctor if you think any prescription or over-the-counter medication may contribute to your flushing symptoms
Clinical trial starting doses The landmark phase 2 trial published in the New England Journal of Medicine randomized 338 participants across multiple dose groups
Hsu PI, Lai KH, Liu CP
