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In colorectal cancer patients treated with the FOLFOX regimen (fluorouracil, calcium folinate combined with oxaliplatin), platinum residues remain detectable in dermal collagen fibers up to 60 months post-withdrawal, mediating persistent, distally distributed neuropathy via damaging cutaneous sensory nerve fibers (Cao et al

The Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study found that youth (aged 10 to 17 years) with T2DM experienced a 20% to 35% annual decline in -cell function, which is significantly higher than the ~7% decline seen in older individuals [43-45]

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scRNA-seq libraries were evaluated and quantified by Agilent Bioanalyzer using High sensitivity DNA kit (#5067-4626) and Qubit (ThermoFisher Scientific, #Q32851)