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Though rare when metformin is taken appropriately, lactic acidosis can be life-threatening

Studies have indicated that bloodletting at the Hand Twelve Jing-Well Points in TBI animal models can yield neuroprotective effects (Liu et al., 2021)

PRO overlap statistics ranged from 0.52 to 0.59 and from 0.60 to 0.70 for randomly selected patients with high versus medium and low BSA, respectively, indicating patients with high and medium BSA are likely to have similar levels of disease burden, and patients with high BSA are slightly more likely to have higher disease burden than those with low BSA

AEs, serious AEs, AEs leading to discontinuation, AEs reported in 10% of participants in any trial and safety focus area AEs are detailed in Table 3