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Further research is needed to determine whether oxidative stress is a driver of lipedema or a consequence of the expanding, hypoxic adipose tissue

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While it is perhaps somewhat surprising that no group differences in metabolite concentrations were found, either for GABA (as has been shown before) or for GSH, we note that autism is an extremely heterogeneous condition, and that group differences, if present, may be small and relatively uninformative in understanding the broader autism phenotype(Loth et al., 2021)