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Blood samples were immediately centrifuged, and plasma was transferred to pre-prepared tubes containing acetonitrile and an internal standard of Nle-YI-(6) aminohexanoic amide, 100 g/ml in isotonic saline

By early 2025, FDA had issued draft guidance on AI model credibility (for drug submissions) ( [5] ) and even collaborated with the European Medicines Agency to publish Guiding Principles of Good AI Practice in Drug Development (January 2026) ( [21] )

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The medication reduces LDL (bad) cholesterol by 515%, increases HDL (good) cholesterol, and lowers triglycerides by up to 20% in many patients