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Off-label Administration Intranasal administration (compounded): Due to patient preference for non-injectable options, compounding pharmacies frequently formulate PT-141 as intranasal sprays

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The most common effects are: Nausea, particularly in the first few weeks after a dose increase Vomiting (less common) Diarrhea or constipation Reduced appetite (this is the desired effect, but it can feel unfamiliar) Most side effects are temporary and improve as your body adjusts