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Numerous factors influence its level, including kidney function, age, gender, diet, composition of the intestinal microbiota, and liver FMO activity

In the Pancreas: GLP-1 stimulates insulin secretion in a blood glucose dependentmanner hence decreasing B cell over function, enhancing Beta-cell survival rate, decreasing B- cell apoptosis and preserving B-Cell mass

Some patients prefer tablets because they: Do not like injections or needles Travel frequently Prefer a daily medication routine Want an alternative to self-injecting each week Others may choose to remain on injections because they prefer the convenience of a once-weekly treatment schedule

Grande MT, Pascual G, Riolobos AS, Clemente-Lorenzo M, Bardaji B, Barreiro L, et al