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Codeine belongs to a group of medicines called opioid analgesics which act to relieve pain.Paracetamol is another analgesic to relieve pain

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Sudden opioid withdrawal can be severe, and you may need to go to the hospital

Conclusion and perspectives In summary, we begin with the key role of changes in synaptic plasticity in sustained antidepressant effect, focus on synaptic plasticity, and followed by a discussion of the modulation of synaptic plasticity by neurexins to demonstrate the potential and feasibility of studies of sustained antidepressant effect through the modulation of synaptic plasticity by neurexins