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In parallel, these peripheral inflammatory signals and microbial metabolites can breach the bloodbrain barrier (BBB) or activate afferent vagal pathways, leading to neuroinflammation in metabolic brain centers such as the hypothalamus and nucleus tractus solitarius (NTS) (224)

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Chimentao RJ, Kirm I, Medina F, Rodriguez X, Cesteros Y, Salagre P, Sueiras JE, Fierro JLG: Sensitivity of styrene oxidation reaction to the catalyst structure of silver nanoparticles