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142 Conclusions The COVID-19 pandemic has highlighted the critical need for new drugs to complement existing therapies

Referring to one of the largest studies, Chwistek said: "What's new here is the consistency across tumour types, and data this large and this consistent warrant a prospective randomised trial."

One of the most notable investigations, the STEP 1 trial published in The New England Journal of Medicine, reported that participants receiving weekly GLP1-S alongside lifestyle interventions experienced an average 14.9% decrease in body weight across 68 weeks[7][8]

The 1.125mg microdose allows these patients to introduce tirzepatide gradually, building tolerance before stepping up to 2.5mg