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But the weight loss process itself can trigger inflammatory responses, particularly in joints and connective tissue as the body adapts to carrying less weight

CD36, a membrane transporter is an important gustatory lipid sensor which also facilitates digestion and further feeds back satiety to the brain [49]

The researchers proposed that the effects in skeletal muscle and the brain are driven by the sensory characteristics of EGCG, specifically its astringency, which is distinct from its bitterness