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Preclinical studies have described the role of Vitamin E in AD: it seems to reduce transepidermal water loss (TEWL), which is associated with AD pathogenesis, and to induce the expression of the transglutaminase-1 gene, involved in terminal differentiation of keratinocytes and in the formation of the stratum corneum (8385)

Cancer Biol Ther 13:13551373 DiNicolantonio JJ, McCarty MF, OKeefe JH (2022) Nutraceutical activation of Sirt1: a review

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Through its modulation of calcium channels, promotion of bone healing, and protection against oxidative stress, BPC-157 may contribute to restoring proper calcium balance in the body