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Reductions in blood glucose together with increased energy expenditure (EE) and decreased food intake, resulting in loss of fat mass, were reported for a different dualAG (chimeric GLP-1/GCG peptide) following one-month treatment 9 and for BI456906 dualAG in DIO mice treated during 4 weeks and in phase 1 and 2 trials 10,11
This could mean men who are hesitant about injections may represent a significant opportunity for oral GLP-1 treatments
Dev Disabil Res Rev 16:144153 Heinecke JW, Rosen H, Suzuki LA, Chait A (1987) The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells
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