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Complex cold-chain logistics and stringent storage requirements for biologic injectables present operational hurdles for home delivery networks

Creatine is transported in blood as a free substance, and is rapidly taken up by extra-intestinal tissues and cells (e.g., liver, skeletal muscle, brain, kidneys, testes, and other tissues and cell types) via CreaT1, and by testes and brain also via CreaT2 (Bala et al

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So, while they show promising results so far, whether this effect translates to humans, needs more research to answer