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In this context, fibroblast growth factor 21 (FGF21) analogues are attractive because they target multiple components of MASH biology simultaneously, with potential to improve steatosis, inflammation, fibrosis, and broader cardiometabolic risk

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The total number of pluripotent NSCs (Sox2 + cells), quiescent NSCs (Sox2 + S100B + cells) 43,44 , astrocytes (S100B + cells), and INPs (Tbr2 + cells) were assessed in SGZ immediately following IH 10 (Fig