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Stress management through meditation, breathing exercises, or journaling also reduces cortisol, which can worsen intestinal inflammation and diarrhea

3a,b,d,e)

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Patients frequently seek medical attention only after symptoms substantially impair quality of life, by which point tissue injury may be established, such as lupus nephritis in SLE, pericarditis in RA, or thromboembolic complications in Crohns disease [25, 26]