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With respect to definition of controls, most studies recruited healthy children with no information about family history of autism spectrum disorders, although, four studies did ensure that controls did not have either a family history or sibling with autism [70, 75, 77, 87] and one screened for autism traits [59]

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The sources, composition, and properties of INPs, especially biological ones, are not well understood, leading to climate model inaccuracies in representing ice-containing clouds and uncertainties in cloud phase partitioning and radiative transfer 1,6