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Fasting glucose normalization, improved insulin sensitivity, and better lipid profiles were observed across dose groups, with particular significance at 4mg and above

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63 Furthermore, BCAT 1 is selectively upregulated in isocitrate dehydrogenase (IDH) wild-type (WT) GBM, and -ketoglutarate (-KG) mediates cell death in BCAT 1-deficient IDH WT GBM