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Studies have explored its effects on pancreatic beta-cell function, lipid metabolism, and inflammatory pathways, with particular emphasis on its ability to restore metabolic homeostasis

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In a typical case, the former will show typical melanocytes with an increased volume of melanin pigment that can be distributed throughout the epithelium and the latter will show increased melanin deposition along the basal cell layer, atypical melanocytes with nuclear pleomorphism, hyperchromatism, and the absence of rete ridges in the affected tissue