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Roofthooft DW, van Beynum IM, de Klerk JC et al , Limited effects of intravenous paracetamol on patent ductus arteriosus in very low birth weight infants with contraindications for ibuprofen or after ibuprofen failure

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AS-IV modulates the Akt/PDE3B pathway to inhibit cAMP accumulation, thereby suppressing lipid catabolism, which is beneficial for limiting liver lipid deposition and reducing excessive hepatic glucose production (Zhou et al., 2017)