Acidic pH impairs the activity of the mitochondrial L-2-HG removal enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) and enhances the protein stabilization of HIF-1, leading to its escape from the degradation pathway 90
Papazian, Irini, Eleni Tsoukala, Athena Boutou, Maria Karamita, Konstantinos Kambas, Lida Iliopoulou, Roman Fischer, et al
Works well
Aqua, Centella Asiatica Leaf Water, Butylene Glycol, Dipropylene Glycol, 1, 2-Hexanediol, Hydroxyethyl Urea, Hydroxyacetophenone, Propanediol, Glycerin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glutathione, Arginine, Carbomer, Niacinamide, Cellulose Gum, Disodium EDTA, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Polysorbate 60, Sorbitan Isostearate, Glyceryl Acrylate/Acrylic Acid Copolymer, Xanthan Gum, Inulin, Cellulose, Fructose, Glucose, Polyglucuronic Acid, Sodium Hyaluronate, Squalane, Beta-Glucan, Asiaticoside, Madecassic Acid, Asiatic Acid, Caprylic/Capric Triglyceride, Hippophae Rhamnoides Fruit Extract, Melaleuca Alternifolia Leaf Extract, Hydrolyzed Collagen, Hydrogenated Lecithin, Artemisia Annua Extract, Nelumbium Speciosum Flower Extract, Oryza Sativa Extract, Saccharomyces Ferment, Solanum Melongena Fruit Extract, Glyceryl Stearate, Cholesterol Ingredients may change
