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Expression of GluR2 induced by the Sindbis virus injected into the subarachnoid space partially recovers PF-PC synapse formation, and alleviates motor dysfunction in GluR2 null mice [25, 58]

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As mitochondria fail to maintain cellular energy, neuronal survival is compromised, and apoptotic pathways are activated (Davidson et al., 2001) (Figure 1)

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doi: 10.1139/apnm-2016-0550 229

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