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Further, these spectra displayed a strong band in a spectral range of 500530 cm 1 that was assigned to two partially overlapping bands: The (S-S) of GSSG centred at 508 cm 1 and (S-N) of GSNO at 522 cm 1

Mannitol, with a cross-sectional hydrated diameter of 6.5 is a small solute that is used as a marker of total intestinal surface area available for absorption, whereas lactulose (with a larger cross-sectional diameter of 9.5 ) is used to assess the paracellular permeability through the tight junctions normalized to the total available intestinal surface [32], with results expressed as a ratio of the permeability of mannitol to lactulose

Moderate responders form the largest group, experiencing significant improvement between weeks 3-6