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Silybin alleviates hepatic steatosis and fibrosis in NASH mice by inhibiting oxidative stress and involvement with the nfb pathway

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However, even while consumption levels are optimal, choline depletion may occur locally in specific disease contexts, such as within the tumor microenvironment or at sites of infection by choline-consuming pathogens (63) or systemically, such as in critically ill patients on parenteral nutrition (62)