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Over the past decade, peroxisome proliferator-activated receptor- coactivator-1 (PGC-1) has been demonstrated as a key transcriptional co-activator, providing a mechanistic insight into nuclear regulatory pathways in the biogenesis of mitochondria in skeletal muscle [7-9]

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Inhibition of cellular and systemic inflammation cues in human bronchial epithelial cells by melanocortin-related peptides: mechanism of KPV action and a role for MC3R agonists