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The liver continues to produce bile, and these medications primary actions on blood sugar and appetite are not directly dependent on the presence of a gallbladder

10.1016/s1875-5364(23)60403-0 37 FanJ

If 500 mcg EOD is not producing noticeable effects after a reasonable trial period: Increase to 750 mcg EOD (22.5 units) If still insufficient, increase to 1 mg EOD (30 units) Wait 5 to 7 days between any dose changes to accurately assess your response before adjusting further Do not rush this phase

Support for weight goals : While not a quick fix, Vitamin B12 for weight loss can be part of a plan that includes healthy eating and movement