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Sci Rep (2015) 5:12898.10.1038/srep12898 59 UdagawaNTakahashiNAkatsuTTanakaHSasakiTNishiharaTet alOrigin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells