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The methodological approach was designed to address cellular and systemic effects, utilizing a range of established biochemical and histological techniques

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks (vol 123, pg 1213, 2005)

Research has shown that etoricoxib rapidly and selectively inhibits COX-2, and its efficacy in terms of treating various clinical manifestations of GA, including pain and inflammation, is comparable to that of indomethacin (210)