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The FDA also approved Ozempic in early 2025 to treat kidney disease

In Diverse Therapeutic Strategies Targeting TMAO, we curated the most pertinent preclinical and in vitro studies on TMAO, emphasizing findings associated with TMAO-induced cell death to deliver a thorough summary of its role in the development and progression of diseases along the gut-organ (lung, pancreas, heart, kidney, and brain) axis

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coli) causes ferroptotic cell death of erythrocytes by inducing the Fenton reaction to release ROS and increase internal iron levels (Yang M