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The presence of AGE in ovarian tissue, together with an altered metabolic profile and elevated testosterone levels therefore provides evidence for a double effect of the AGE taken with the diet on reproductive and metabolic function [39]

(2) BPC 157 promotes the vessel relaxation mainly acting on vascular endothelial cells but much less on vascular smooth muscle cells

Overall, existing clinical research provides compelling evidence that RCD-related molecular signatures and circulating DAMPs hold significant promise as predictive and monitoring biomarkers in melanoma immunotherapy, warranting further prospective validation ( Table 1 ) (197, 198)

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