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Androgen receptor and Wnt signaling operate as key stimulators of HF development in FGF5 KO sheep To explore the causes of increased wool and active hair-follicle density in FGF5 KO sheep, we tested the expression levels of testosterone and DHT that cause androgenetic alopecia in the skin tissue of the KO and control groups by ELISA

When the GSH binding site was identified, we initially predicted that our GSH-bound OsDHAR structure may represent a GSH binding site that existed prior to covalent bond formation with Cys20 (Fig