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Successful combination therapy requires adequate protein intake, typically 1.6-2.2 grams per kilogram of body weight, and consistent resistance training to protect muscle mass

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Sources like avocado, olive oil, fatty fish, and nuts provide essential fatty acids without adding excessive volume to meals

A deeper understanding of the mechanisms of action of small molecules, the exact sites of action, the necessary dose to achieve the desired effect, and the optimal time to start antioxidant therapy for preventive or curative effects may provide a rational approach that may result in greater pharmacological and clinical success in low-molecular-weight antioxidant therapy