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While neither tirzepatide nor niacinamide requires routine dose adjustment for hepatic impairment, patients with severe liver disease should be monitored closely if treatment is deemed necessary by the prescribing provider

Hydro-distension (filling the bladder with saline while under anaesthetic), which is undertaken as part of diagnosis, can also relieve symptoms in about half of patients

This class of medications has demonstrated effectiveness for substance-use and binge-eating disorders

At the time of that approval, Health Canada said eight other submissions remained under review [Source: globalnews.ca/news/11820779/canada-approves-1st-generic-ozempic-market/]