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Given the higher risk associated with SO for functional capacity decline, cardiovascular health, and all-cause mortality, it is anticipated that SO may result in more severe public health consequences than obesity alone [10]

Both of the compounds produced nearly the same effects when it came to inflammation and hyperalgesia in a rat model of cyclophosphamide induced HC, MV8608 arrested hemorrhage formation and the infiltration of neutrophils while MV8612 reduced the weight of the bladder and the nociception score (Santos et al., 2010)