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TMAO may contribute to the development of MAFLD through the following mechanisms (Figure 1)

In particular, GLP-1 reduces blood glucose and body weight [3]

[31] Other good sources of vitamin D are foods like wild salmon and cod liver oil

Retatrutide is an investigational triple incretin receptor agonist targeting GLP-1, GIP, and glucagon receptors to reduce appetite and body weight, while tesamorelin is a growth hormone-releasing hormone analogue that stimulates pituitary GH release to reduce visceral fat, primarily in HIV-positive patients with lipodystrophy