In pigs, which are considered tolerant concerning iodine excess, high iodine doses up to 10 mg/kg caused a significant downregulation of NIS in the thyroid gland and, simultaneously, it decreased mRNA expression of clue antioxidative enzymes, such as SOD and GPx, either in the liver or in the kidney or in muscles (target tissues of thyroid hormone action), however without affecting lipid peroxidation [196]
Ryan G, Jobe L, Briscoe T
Drug created on June 13, 2005 07:24 / Updated on January 20, 2014 14:07 Chen, R.G., et al., 1993
Professional guidelines from organizations such as the American Gastroenterological Association and the Endocrine Society recommend that weight management treatment, including pharmacotherapy, be provided within the context of ongoing clinical care with regular monitoring