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Copper is involved in melanin synthesis (hair pigmentation) and is a cofactor for enzymes involved in keratin cross-linking

Clinical Considerations Disease-associated Maternal and/or Embryofetal Risk Poorly controlled diabetes in pregnancy increases the maternal risk for diabetic ketoacidosis, preeclampsia, spontaneous abortions, preterm delivery and delivery complications

GHK-Cu is studied in research models involving copper peptide signaling, extracellular matrix pathway behavior, collagen-associated biology, dermal response systems, oxidative stress pathways, and cellular repair-associated signaling

Patients frequently present with loud snoring, witnessed apneas, and excessive daytime sleepiness, although symptom severity may vary